Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
ESCA | rs2642978 | chr1:247156066 | C/T | 1.73E-7 | 176 | 3.87 | 20.3 | 13.03 | KM Plot |
ESCA | rs2730103 | chr18:32201608 | T/G | 7.87E-5 | 184 | 13.37 | 13.03 | 6.43 | KM Plot |
ESCA | rs2730114 | chr18:32125273 | G/A | 0.000103 | 181 | 13.4 | 12.95 | 6.43 | KM Plot |
ESCA | rs2730130 | chr18:32204694 | C/T | 7.87E-5 | 184 | 13.37 | 13.03 | 6.43 | KM Plot |
ESCA | rs2735806 | chr14:105595101 | A/G | 6.97E-6 | 182 | 1.57 | 22.72 | 13.03 | KM Plot |
ESCA | rs2816604 | chr14:105715327 | A/C | 4.98E-5 | 180 | 13.67 | 12.78 | 5.7 | KM Plot |
ESCA | rs2818872 | chr1:247166017 | A/G | 1.65E-7 | 177 | 3.87 | 16.7 | 13.03 | KM Plot |
ESCA | rs2818874 | chr1:247170629 | T/C | 1.71E-7 | 176 | 3.87 | 20.3 | 13.03 | KM Plot |
ESCA | rs2818893 | chr1:247160495 | A/C | 1.49E-7 | 178 | 3.87 | 18.5 | 13.03 | KM Plot |
ESCA | rs2838505 | chr21:45583903 | A/G | 5.55E-6 | 184 | 2.93 | 12.87 | 13.35 | KM Plot |
ESCA | rs2839134 | chr21:47591782 | C/T | 4.89E-5 | 184 | 3.93 | 13.63 | 13.18 | KM Plot |
ESCA | rs28419258 | chr8:41350055 | C/T | 1.89E-7 | 182 | 13 | 17.27 | 2.7 | KM Plot |
ESCA | rs28449404 | chr4:10019678 | C/G | 1.39E-5 | 183 | 13.07 | 13.87 | 7.93 | KM Plot |
ESCA | rs28478353 | chr19:5071460 | G/A | 3.46E-6 | 181 | 13.07 | 14.82 | 2.93 | KM Plot |
ESCA | rs2849489 | chr18:32141140 | C/A | 6.88E-5 | 181 | 13.4 | 11.93 | 5.4 | KM Plot |